The Role of T Lymphocytes in Bone Remodeling

Bone remodeling is a tightly regulated resorption and formation of bone matrix for physiological processes or to maintain function. involves the synchronized differentiation activity bone-related cell types including matrix-depositing osteoblasts, matrix-resorbing osteoclasts, collagen/extracellular matrix-producing chondrocytes, progenitors these types. T B cells are adaptive immune that can influence by directly regulating function under normal pathophysiological conditions. The specific mechanisms through which control not well defined. Here, we review impact their products on during remodeling. Synthesizing new connections highlighting potential may promote additional avenues study elucidate full role play in homeostasis.